{"id":1399,"date":"2020-07-01T00:00:01","date_gmt":"2020-06-30T15:00:01","guid":{"rendered":"http:\/\/garden-of-ethel.com\/?p=1399"},"modified":"2020-07-01T00:00:01","modified_gmt":"2020-06-30T15:00:01","slug":"mangos_anemia_12thday","status":"publish","type":"post","link":"https:\/\/garden-of-ethel.com\/en\/blog\/2020\/07\/mangos_anemia_12thday.php","title":{"rendered":"Mango\u2019s Anemia 12th day to last day"},"content":{"rendered":"

See here for 1st & 2nd day<\/a>
\nSee here for 3rd day<\/a>
\nSee here for 4th day<\/a>
\nSee here for 5th day<\/a>
\nSee here for 6th day<\/a>
\nSee here for 7th day<\/a>
\nSee here for 8th day<\/a>
\nSee here for 9~11th day<\/a><\/p>\n

<\/p>\n

On the morning of 9\/13, we took Mango to UW-vet for blood test. We have been suspecting he may have teeth problem. We did detailed scope check of his teeth under mild anesthesia, meanwhile, took his blood sample.<\/p>\n

In the afternoon, doctor found a small crack on one of his back molar. Near by the molar, she fond a small inflammation too. She prescribed Meloxicam as pain relief, and switched albendazole to oxibendazole as we asked before.
\nAfter he got Meloxicam, he started eating vegetables. We noticed his speed of eating is quite slow.
\nIt was due to much serious problem than the teeth crack, but we never imagine about it.<\/p>\n

On the next morning, 9\/14, I got a call from vet that informed us Mango’s severe anemia.
\nHis PCV value dropped to 13%. Just a week ago, on 9\/5, it was 22%.
\nAnd this time, not only red blood cell count but also white blood cell count and platelets count were drastically decreasing.
\nBlood cells ware forming clusters, which was not observed on 9\/5.
\nAlso, there was no immature cell in his blood, even his PCV dropped suddenly to this dangerous level.<\/p>\n

Doctor suspected bone marrow decease with auto immune disorder, which we excluded just one week ago.
\nThe change was too sudden to explain otherwise auto immune disorder or toxic.<\/p>\n

We took his bone marrow for pathological analysis.
\nThe result showed desperately small number of mother stem cell.
\nHis mother stem cell had gone, instead, his bone marrow was filled with fat.
\nIt was aplastic anemia, which is quite rare for a rabbit.<\/p>\n

Since Mango was HRS rescued rabbit, the director of Wisconsin HRS tried to search for a case of aplastic anemia in all US HRS network, but he couldn’t find even a single case.<\/p>\n

On the afternoon of 9\/14, Mango started to bleed from his nose.
\nWe had to make a decision for next step.
\nSince Mango was still cheerful and trying to recover, we decided to do blood transfusion from other HRS bunny Angel.<\/p>\n

On evening of 9\/14, we put IV catheter on Mango’s foot and start to give medicine for immune-suppression.
\nWe took 60ml of Angel’s blood and transfused it to Mango until midnight.
\nAfter that, we noticed Angel’s PCV was also 29% (before transfusion), which shows mild anemia too.
\nWe also took other two rabbit’s blood sample (for Petit and Rufus), in order to check their blood count.
\nAt that time, Petit and Rufus’s PCV was middle of normal range, but one week later, Rufus’s PCV dropped 8% from that day.
\nDoctor seriously suspected that our house may have toxic materials.
\nWe doubted carpet cleaner solution (that was for “pet odor”) we sprayed almost three weeks ago, but from the ingredient list the company gave us<\/a> and Material Safety Data Sheet(MSDS)<\/a>, we couldn’t find any toxic ingredient which causes aplastic anemia.<\/p>\n

Mango was in vet for next two days. On the third day morning, his leg with IV catheter got inflammation and his favor was rising up.
\nThey suspected infection from IV catheter and removed it.
\nNow we had to switch oral medication for immune-suppression.<\/p>\n

We took Mango to home, and gave flesh vegetables. He ate a lot!
\nCarrot top — for two carrots,
\nBasil leaves — 2 stems
\nCelery 1\/2 stem
\nPellets 2 tsp.<\/p>\n

<\/object><\/p>\n

He also ate hay, which he didn’t like before.<\/p>\n

<\/object><\/p>\n

I applied “Chi” power to him. After a while, his intestine start to move very actively. I have never seen any of our rabbit’s intestine is moving so fast, with large movements.
\nHis favor and cool down in short period like one hour.
\nThen he took relax posture as he is in safe home.<\/p>\n

\"PICT0044\"<\/a><\/p>\n

On midnight of 10\/18, he ate basil’s stem.
\nHe also ate two dandelion leaves quickly.
\nAfter that, he jumped into his litterbox — then suddenly, he started bleeding from his nose again.<\/p>\n

I couldn’t understand what was going on, Mango was sniffing again and again, and I saw something red was hanging down from his nose holes.
\nI let my room mate wake up and we caught him to check his nose. He couldn’t take his breath because his nose hole was clogged with red rubber-like material. We doubted the material is platelets.<\/p>\n

When a human got bleeding from nose, shocking heels works quite well to stop it.
\n(Usually we hit our heels on a hard wall with our back faced on the wall)
\nWe tried to shock Mango’s heels, and it seems like working even for a rabbit.
\nHis blood stopped, but then his nose holes was filled with the rubber-like platelets.<\/p>\n

He started to breath with his mouth. It looked so difficult for him, and I was afraid that the blood may run into his throat and make his throat clog again.
\nWe decided to suck out his platelets from his nose with my mouth.
\nEventually, that might triggered his pneumonia, since he didn’t have enough white cell.
\nI have never tasted rabbit’s blood, but the taste was quite thin.
\nAt 4 AM, his nose hall was finally cleared out and he start to breath normally.<\/p>\n

He lost so much power during the night and couldn’t eat anything.
\nHe tried to eat his most favorite banana, but he couldn’t manducate it anymore.
\nOn the afternoon, we noticed his nose is bleeding slightly again.
\nHe could drink water with a small syringe.<\/p>\n

On 9\/19, we noticed his breath was making strange noise.
\nIt was Saturday and our doctor was not on call shift.
\nThe director of WHRS suspected that Mango’s lung have water due to high favor, and may be we have to make up our mind.
\nWe made his posture inclined in order to reduce the strange noise.<\/p>\n

\"PICT0048\"<\/a><\/p>\n

<\/object><\/p>\n

It is the last picture of Mango.
\n\"PICT0054\"<\/a><\/p>\n

On Sunday morning, 9\/20, we took Mango to UW-vet again.
\nWe asked hospice care for Mango, but since it was Sunday we couldn’t find any company that rent a oxygen chamber for him.
\nMango was given sedation and looked very calm.<\/p>\n

Since we couldn’t get oxygen chamber, we finally decided to euthanize him.
\nJust after the decision, his body tilted slowly and his breath get larger.
\nBefore we give anesthesia to him, Mango stopped his breath.
\nDoctor gave a shot and his heart stopped soon.<\/p>\n

Mango’s body was donated for necropsy.
\nWe found liver lobe torsion that result in necrosis in the affected lobe.
\nWe don’t know why it happened and why we didn’t find the problem with both x-ray and ultra-sound.
\nLiver lobe torsion in rabbit may cause anemia but not aplastic anemia.<\/p>\n

See this file<\/a> for detailed report.<\/p>\n

\"PICT0056\"<\/a>
\nPlatelets extracted from Mango’s nose
\n\"PICT0058\"<\/a>
\nLast drops
\n\"PICT0060\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

See here for 1st & 2nd day See here for 3rd day See here for 4th day See here for 5th day See here for 6th … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_locale":"en_US","_original_post":"480","footnotes":""},"categories":[11,16,28],"tags":[],"_links":{"self":[{"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/posts\/1399"}],"collection":[{"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/comments?post=1399"}],"version-history":[{"count":0,"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/posts\/1399\/revisions"}],"wp:attachment":[{"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/media?parent=1399"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/categories?post=1399"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/garden-of-ethel.com\/wp-json\/wp\/v2\/tags?post=1399"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}